9/1/2023 0 Comments Ncbi nucleotideHow do you use the default nucleotide database? Do you mainly need quick matches to highly annotated records, or are you trying to find distantly related homologs to coding regions? Please try searching with the test databases and tell us about your experience. Inset: The Feedback button where you can provide your feedback about these databases and how you use BLAST. This page has a possible database option that divides nt into four smaller databases by taxonomic/functional categories. Database selection list on the new test page. Please try the test databases and let us know what you think!įigure 1. To begin getting feedback, we have created a page with four new databases based on taxonomic categories (Figure 1). Re-factoring of the database may be based on one of these strategies and will make use of feedback concerning your BLAST usage. Divide it into several databases by biological or functional categories.Change its composition to improve the quality of sequence entries included.In the not-too-distant future, searching the entire nt database on the web will no longer be possible unless we modify the database scope and composition.īecause of the above concerns, we want to make the default Web BLAST nucleotide database smaller and more efficient. This growth will cause longer search times, reduced capacity, and more delays in updating the database. The default BLAST nucleotide database (nt), the most popular Web BLAST database, is currently 903 billion letters and continues to grow rapidly – doubling in size in the last year. The ongoing sequencing revolution has resulted in exponential growth of the NCBI BLAST databases.
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